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This process, combined with the increase in lean muscle mass, creates a more efficient metabolic state

As a central component of the cell-to-cell and intracellular lactate shuttles, lactate ensures efficient energy distribution from its production sites such as glycolytic muscle fibers to oxidative tissues, including heart, brain, and oxidative muscle fibers, where it serves as a primary fuel for mitochondrial oxidative phosphorylation [233, 234]

Within the mitochondria, glucose, amino acids and fatty acids can eventually be metabolised through a process called cellular respiration, leading to the production of the molecule ATP

The plotter explains why

Tirzepatide produced a mean body weight reduction of 20.2%

For CJC-1295 no DAC, this means the modified GHRH sequence can no longer bind to GHRH receptors on pituitary somatotrophs