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[11] Basen-Engquist, K., & Chang, M

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Factors such as trauma, nutritional deficiencies, irritable bowel disorders, leaky gut, microbiome dysbiosis, and immune dysregulation can all contribute to the generation of ROS, leading to tissue damage and ulcer formation

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While your body can use those amino acids to build its own glutathione later, you lose the benefit of the intact "master antioxidant" entering your system directly