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Exposure to chemicals and other pollutants can increase the demand for the bodys antioxidants, while autoimmune diseases have also been shown to deplete glutathione

The Lymphatic Shunt: By utilizing M-cell endocytosis, the iron avoids the livers hepcidin-driven gatekeeping

Body Areas that Encounter Skin Pigmentation: Areas like elbows and knees are often pigmented, and you also get significant pigmentation on the toes where the footwear could be chafing against the skin

It's an indirect but very real mechanism

Supporting glutathione levels may help the liver work more efficiently, particularly for those exposed to environmental toxins or poor dietary habits