semaglutide vs glp 1 Daniel J Drucker on X: "Developing new more potent GLP-1R molecules or multi-agonists for #Diabetes #Obesity ? Was @novonordisk lucky, very smart, or both, to come up with #Semaglutide Hundreds of new What's the difference—and which one

The GLP-1 revolution is just getting started

On the other hand, some concerns to think about for older adults taking GLP-1s include: Dehydration

That depends on the medicine and how new it is

A consistent model goes with ligation leading to vessel injury, exposure of tissue factors, stasis, thrombosis, hemodynamic changes, arterial hypotension, and in particular, venous hypertension, which approximates values over 20 mm Hg in the inferior caval vein, thereby being roughly four times higher than those in normal rats

These modifications are discussed in research literature for their effect on reducing binding affinity to insulin-like growth factor binding proteins, resulting in extended biological half-life in experimental models

A.KaelberD