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Microdosing GLP-1 means using doses significantly below the approved therapeutic range, but this practice lacks clinical trial evidence and is not approved by the MHRA
This protocol uses lower doses to minimize side effects while establishing tolerance, making it ideal for individuals sensitive to appetite suppressants or those starting weight loss treatment for the first time
doi:10.1093/toxsci/kfi057
Secondary endpoints were also achieved, with 10 mg and 15 mg doses leading to substantial weight loss (up to 63% achieving 20% reduction)
While there were reductions in cardiovascular death (12%) and all-cause mortality (14%), the rates of fatal myocardial infarction (MI) and hospitalization for MI were not significantly different (80)
Presented for research literature review only Joshi UM et al
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