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The study also opens the door for more future research about the administration routes of vitamin B12 and other vitamins

"The data and hypothesis are very intriguing, but much additional investigation is required to determine if this is a real cause-and-effect phenomenon," said Josh Miller, a professor of nutritional sciences at Rutgers University who was not involved with the study

In those patients, addressing the underlying metabolic dysfunction first, through dietary intervention, GLP-1 therapy if indicated, or NAD+ support for cellular energy metabolism, is the clinical priority