The "rapid reversal" group (approximately 10-15% of users) experiences concerning quick benefit loss within weeks of discontinuation, typically involving users who applied very high concentrations creating dependency-like patterns, possessed severe underlying skin conditions requiring ongoing treatment, experienced significant lifestyle or environmental stressors overwhelming skin resilience, discontinued abruptly without tapering from high-dose protocols, or had unrealistic perception inflation during treatment leading to exaggerated reversal perception
Examples include 16 : Endometrial uterine polyps Uterine fibroids (leiomyomata) Endometriosis Congenital uterine malformations Intrauterine scarring and adhesions (synechiae), also known as Asherman syndrome 22 Abnormalities of the cervix, whether congenital or acquired through surgery or dysplasia (a precancerous condition), as well as decreased cervical mucous, can disrupt sperm progression and prevent fertilization
Best sources: Carrots Sweet potatoes Spinach Kale Liver 6
Diabetes medications: GLP-1 agonists and GH secretagogues affect glucose
Baar's team tracked the peptide with an anti-TAT antibody and saw intracellular uptake within 2 to 4 hours of dosing, with it still detectable at 72 hours
An older pill which is an oral retinoid