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This systemic effect simply cannot occur with topical application

Glass Skin Texture: Visibly refines pores and smooths uneven skin texture for a radiant, lit-from-within glow

10.1038/ajg.2013.451 5 AtreyaR.MudterJ.FinottoS.MllbergJ.JostockT.WirtzS.et al (2000)

Results generally last about one week , which is why we recommend weekly sessions initially, then maintenance treatments every 3-4 weeks once you've achieved your desired results

Some sources suggest that freezing reconstituted peptide solution can damage the molecular structure through ice crystal formation

Let the lather sit for a minute before rinsing to allow the AHAs to work their magic