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To provide a more accurate prediction of skin irritancy potential of the test compound, in vitro skin irritation test can include other potential biomarkers
In terms of documented efficacy, this is not a close comparison: GLP-1 S has shown weight reductions in the range of 13-20% of body weight in clinical trials, while AOD-9604s pivotal trial failed to demonstrate a significant effect at that scale
PMID 9655823
Unknown Important limits No established long-term human safety data exists
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