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(2) neuropathological studies identified a schizophrenia-associated reduction of presynaptic markers for GABAergic interneurons in the hippocampus and the intermediate layers of the prefrontal and cingulate cortex, namely reduced expression and/or density of GABA transporters (GAT), glutamic acid decarboxylase GAD67 (but not GAD65), and the Ca 2+ -binding protein parvalbumine