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Researchers running a full SURPASS-2 ladder (2.5 5 7.5 10 12.5 15mg, one event each) consume 52.5mg from a single 60mg pen, leaving 7.5mg headroom for a confirmatory replicate at the lower end

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Tirzepatide itself is a dual GIP and GLP-1 receptor agonist

This multi-target mechanism distinguishes it from earlier investigational peptides that primarily target one or two metabolic pathways

Amycretin is Novo's dual GLP-1 + amylin molecule with both oral and injectable programs

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