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The exenatide group in this study, however, showed a significant increase in the mean cardiac output by 1.2 L/min, a reduced total peripheral resistance by the mean of 120 dyns/cm 5 , and a significantly reduced urinary sodium: creatinine ratio without a significant change in the BP [39]
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However, these conformational changes do not occur in all microbial GGTs owing to the absence of lid loop as seen in Bacillus species