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doi:10.3389/fphar.2025.1551843
From a single GLP-1 receptor agonist to dual agonists (tirzepatide) to triple agonists (retatrutide) to a quintuple agonist, the drug design is growing more sophisticated
Clinical Practice Statement: Pharmacotherapy for Obesity
, use of volatile anesthetic agents and opioids can precondition the heart by modulating mitochondrial potassium channels and reducing ROS generation ( While excellent recent reviews have summarized mtDAMP biology in sterile inflammation and systemic diseases ( Figure 1
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