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Facial flushing results from melanocortin-mediated nitric oxide release causing peripheral vasodilation the same mechanism that produces erections as a side effect of Melanotan-2
McConnell added, "Not knowing the safety of the drug, I think [patients] should be cautious and try not to get pregnant while taking it because we don't know the long-term effects." Both doctors recommended the use of "backup barriers," or extra contraceptives, while taking GLP-1 drugs
Blood sugar and hydration
Wharton S, Freitas P, HjelmesTh J, Kabisch M, Kandler K, Lingvay I, et al