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When this benefit is removed, oral semaglutide is more costly and no more effective than other second-line treatments available for patients with type 2 diabetes mellitus (T2DM)

If side effects persist beyond week 3 or become severe, your PlexusDx clinical team can explore dose adjustments or alternative formulationsoral semaglutide sometimes causes fewer gastrointestinal effects for certain individuals, though it typically starts at a higher price point ($289/mo)

The extremely long half-life (~12 days) raises additional concerns about compound accumulation with chronic daily dosing

He was prescribed the drug for kidney disease and sleep apnea

Moniz T, Lima S A C, Reis S

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