Pomegranate peel extract prevents liver fibrosis in biliary-obstructed rats
Immunovant Sector: Pharmaceuticals and biotechnology (autoimmune and immunology therapeutics) HQ: 320 W 37th St., New York, NY Year Founded: 2018 Key Leaders: Eric Venker, MD, PharmD, CEO Number of Employees: 362 Stage: Public Financial Snapshot: $3.83 billion Notable Investors: SG Americas Securities, Roivant Sciences, RTW Investments, and BVF Partners Key Products: Immunovant is developing Batoclimab, an FcRn-targeting monoclonal antibody for autoimmune diseases (MG, TED, Graves disease), which is in Phase 3 registrational trials
SCFAs bind G protein-coupled receptors, the most studied of which are free fatty acid receptors 2 (FFAR2, also known as GPR43) and 3 (FFAR3, also known as GPR41)
For a patient with obesity-related complications who needs treatment in 2026 or 2027, the practical answer to "Ozempic or retatrutide?" is: Ozempic, because retatrutide isn't available
The abuse of alcohol causes steatosis/liver injury as well as malnutrition leading to deficiencies in vitamin (B1, B2, B6, B12, C, K, A, and D) and minerals (selenium, zinc, magnesium, iron, and phosphorus) that significantly affect cellular metabolism as well as the epigenetic profile
I still have a 33 BMI