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Renal protection with glucagon-like peptide type 1 receptor agonists In CVOTs of arGLP1 renal outcomes were prespecified as key secondary outcomes in 4 studies done with liraglutide, subcutaneous semaglutide, dulaglutide, and efpeglenatide,58,59,63,64 or were collected as safety parameters in other studies.60 Overall, the prevalence of CKD stage 3 in these studies was low (2030%) (Table 1)
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This is a direct consequence of GLP-1 receptor activation in the gut, which slows gastric motility
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213 In recent years, the NADs sequence design process has been accelerated by the development of advanced bioinformatics tools, considerably reducing the time and costs
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