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The medication is not recommended during pregnancy or breastfeeding
GLP-1s are generally well-tolerated with manageable side effects
Typical genes, such as OCTN2 (encoded by SLC22A5) and /or BBD (encoded by BBOX1), regulated by PPAR play regulatory roles in the cellular fatty acid uptake, fatty acid activation, intracellular fatty acid transport, and -oxidation of mitochondrial and peroxisomal fatty acids (84)
The mechanisms differ slightly between medications, but both slow gastric emptying and alter gut hormone signaling in ways that can trigger nausea
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