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Eligibility assessments, dosing decisions, and continuation protocols are managed within a clinical framework that prioritizes patient safety and metabolic appropriateness

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Please refer to the formulary HERE for additional details

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A Wnt antagonist, Frzb (also known as SFRP3 ), is expressed on the opposite side of the developing organ of Corti, possibly creating a gradient of active Wnt5a signaling across the sensory domain