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Furthermore, NF-B induces vasoactive factors including interleukin-6 (IL-6) and intercellular adhesion molecule 1 (32), which promote endothelial dysfunction and accelerate diabetic cardiomyopathy progression

In addition, 3.1% to 3.8% of patients receiving Ozempic stopped treatment due to gastrointestinal side effects compared to 0.4% of the placebo group

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Estimation of the BDNF protein Brain-derived neurotrophic factor (BDNF) levels were measured using enzyme-linked immunosorbent assay kits according to the manufacturers instructions

In CKD, reduced renal function limits TMAO clearance, whereas excessive levels in metabolic syndrome increase the risk of T2D and cardiovascular diseases