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Data availability The data generated in this study are publicly available in Gene Expression Omnibus (GEO) (RRID: SCR_005012)

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Participants were randomized to placebo, dulaglutide 1.5 mg (active comparator), or one of four retatrutide dose groups (0.5 mg, 4 mg, 8 mg, 12 mg)

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This is the design intent: better cellular potency per microgram

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