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Route of administration and lifestyle fit For patients, the biggest differences lie in how these medications fit into their current lifestyle and life stage: Oral GLP1s require daily dosing Injectables are once weekly but require needles Roughly one in four adults has needle aversion, and oral options may open the door for patients previously unwilling or unable to use injectables

Broad, clearly described supporting formula

Due to this variability, there is no standardized treatment protocol, and management remains largely individualized

In an as-treated (AT) analysis, follow-up was also censored at study-drug discontinuation or comparator-initiation

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Hypoglycemia risk is real, and training without fuel when you have already been eating less all day is a recipe for poor performance and excessive muscle breakdown