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Free Radic Res 52 , 288303, (2018)

Taking it too close to meals or supplements may reduce its effectiveness

doi: 10.1016/j.foodchem.2003.09.023 12

RIPTACs are unique heterobifunctional small molecules capable of targeting and selectively killing cells via the formation of a ternary complex between a cell type-specific TP (target protein), the RIPTAC molecule, and a pan-essential effector protein (EP) that is required for cell survival

Moreover, inhibition of PFKFB3 by 3PO has been shown to exert anti-inflammatory and antifibrotic effects on experimental lung fibrosis in mice [12]