GLP-1 (Glucagon-Like Peptide-1) is secreted by intestinal L-cells in response to nutrient intake
Most side effects are gastrointestinal and occur most frequently when you first start the medication or when your dose is increased
Once you know the big pharmaceutical companies are spending a lot of money looking for glucagon receptor antagonists and testing them, and GIP receptor antagonists and testing them, it requires a lot of gusto, a lot of lunacy and craziness to say, nah, I believe all these big pharmaceutical companies are wrong, my lab is doing the opposite. But now, the sentiment has drastically shifted and many companies are looking to co-agonist drugs to achieve over 20%, or even close to 30% weight loss
However, GLP-1 medication comes at an additional cost
This not only enhances skin health by reducing oxidative damage but also promotes a youthful appearance by combating signs of aging
For many patients, that difference is the entire conversation