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The peptide approach to inflammation aligns well with what many in the longevity peptide community consider optimal: reducing harmful chronic inflammation while preserving beneficial acute inflammatory responses
Electrophysiology in slice preparations is the closest thing to the historical literature, since the original observations were EEG-based
But here are some general guidelines: Severe deficiencies: Daily shots for 1 week, then weekly shots until levels normalize Moderate deficiencies: Weekly shots until the deficiency is corrected Maintenance dosing : Monthly shots to keep B12 levels optimal Its definitely possible to take B12 shots too often
When GHK-Cu is injected, free copper can temporarily separate from the peptide backbone before rebinding in tissues
Most vitamin B12 injections and oral supplements in the United States use a form of vitamin B12 called cyanocobalamin, however this form of vitamin B12 has the toxin cyanide connected to the molecule
PMID 12361895.
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