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From there, the dose can be increased in 2.5 mg increments every four weeks, following this general path: Month 1: 2.5 mg (Initiation) Month 2: 5 mg (First therapeutic dose) Month 3: 7.5 mg Month 4: 10 mg Month 5: 12.5 mg Month 6+: 15 mg (Maximum dose) Tirzepatide Titration Comparison Table Key Takeaway: The 4-week rule is a safety standard designed to protect your digestive health

Headache Infrequent and usually limited to the initial treatment period

Contact your GP, call NHS 111, or seek urgent care if you notice : Significant swelling, warmth, or redness spreading beyond the injection site Signs of infection, such as pus, increasing pain, or fever A hard, painful lump that does not resolve within a few weeks Severe or persistent abdominal pain, with or without vomiting seek urgent medical assessment, as this may require evaluation for serious conditions such as pancreatitis An allergic reaction, including rash, difficulty breathing, or swelling of the face or throat this requires immediate emergency care (call 999) Beyond local reactions, retatrutide like other agents in its class may cause systemic gastrointestinal side effects such as nausea, vomiting, and diarrhoea, particularly during dose escalation

Jurisdiction and transitional period The UPC has exclusive jurisdiction over EPs and UPs

Defective Items & Others If you receive a defective item, you can contact the seller directly if you are able to speak Korean