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Thus, they modulate the intestinal microbiota by stimulating the production of catecholamines and their metabolites as well as affecting the inflammatory response [8, 154, 155]

Likewise, the helix IVECL2helix V region displays a high degree of structural similarity between the two inactive receptors

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As a result, l-DOPA crosses the bloodbrain barrier and gets converted into dopamine in the brain, which could reduce the symptoms associated with PD (171)

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