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Annexin V binds phosphatidylserines that translocate to the outer leaflet of the membrane during early apoptosis 61 , whereas 7-AAD is a membrane-impermeable DNA dye that labels cells with compromised membrane integrity, identifying cells undergoing lytic forms of cell death such as necrosis, secondary necrosis and pyroptosis 62,63
Double-blind trials and post hoc analyses of those results have shown positive applications
2009 FebApr;30(1-2):112
Smaller peptides have fewer vulnerable residues and less complex three-dimensional structures that can unfold
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