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Blog Posts: Insulin Resistance: Are You at Risk for Developing Diabetes
If your priority is no injection at all, ultrasound cavitation or fat freeze deserve a serious look
Friedrichsen M, Breitschaft A, Tadayon S, Wizert A, Skovgaard D: The effect of semaglutide 2.4 mg once weekly on energy intake, appetite, control of eating, and gastric emptying in adults with obesity
These medications work by mimicking the bodys natural GLP-1 hormone, which reduces appetite, increases satiety, slows gastric emptying, and improves insulin regulation
This saturation curve explains why dose escalation beyond 500mcg produces diminishing returns
Retatrutide: Complication Focus TRIUMPH-4: Obesity + knee osteoarthritis (445 participants) TRIUMPH-2: Obesity + type 2 diabetes TRIUMPH-6: Weight maintenance trial Advantage: Multiple complication-specific trials could lead to broader label (obesity + OA + OSA indications)
