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Anything that is severe, worsening, or systemic is a reason to stop and seek a clinician rather than to adjust the protocol

They were all healthy individuals without any systemic diseases and without any habits like smoking, alcoholism, etc

([BMI] 30 kg/m2)(BMI 27 kg/m230 kg/m2)In some embodiments, the dosage is administered to individuals with any of the above-mentioned indications