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Mechanistically, irradiation-associated NF-B activation can transcriptionally upregulate miR-221/222, which suppresses Syndecan-1 (Sdc1) to weaken epithelial barrier integrity and aggravate mucosal injury 63,64
This natural appetite suppression makes overeating less likely because the motivation simply isn't there
doi:10.3322/canjclin.35.3.130
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Of course, if someone tells you that your body is inadequate, it is going to impact your self-image