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There have been several cardiovascular outcomes trials (CVOTs) involving GLP-1RAs, which have supported the overall cardiovascular benefits of these drugs

D-2-naphthylalanine (D-2-Nal) at position 3 and D-phenylalanine (D-Phe) at position 4 provide protease resistance and contribute to receptor binding affinity

Better-tolerated fat sources include: Avocado Nuts and seeds Olive oil Fatty fish like salmon or sardines Smaller amounts of fat spread throughout meals are usually better tolerated than one large, high-fat dish

And both are now available in India under medical prescription