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doi: 10.1016/j.jhep.2023.07.017 10

Consider alternative approaches including adjuvant therapy and newer or second-generation antipsychotics such as clozapine

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The optimal amount depends on your typical dose range

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Notably, stimulation of neuroblastoma cells with ANG II with the CB1 antagonist SR141716 inhibited ANG II-induced mitogenic signaling, whereas co-treatment with the CB1 agonist HU210 enhanced this response ( Stellate cells are also present in the intestines, where they are referred to as intestinal subepithelial myofibroblasts (ISEMF) ( Therefore, targeting CB1 receptor activity to modulate the molecular mediators of the RAS may hold therapeutic potential in preventing or attenuating intestinal fibrosis in IBD