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The active ingredient, Glimepiride, works by binding to specific receptors on the surface of pancreatic beta cells

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In male elite climbers, the resting serum cortisol and plasma adrenocorticotropic hormone (ACTH) levels taken at 07:0007:30 did not change at 5200 m extreme altitude camp compared with those at sea level 6

These medications should be avoided during pregnancy and breastfeeding

In accordance with Dong et al