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Fabrikant J, Touloei K, Brown SM
However, people with pre-existing macular edema or other retinal conditions need closer observation
A randomised controlled trial in 1,897 individuals living with type 2 diabetes compared the impact of three doses of tirzepatide (5mg, 10mg, and 15mg) compared to a once-weekly injection of 1mg semaglutide (Ozempic) on blood sugar levels
Many compounds that looked effective in animals later failed human trials or revealed safety concerns
Gellmans company Longevity Biotech now has a drug candidate that activates both GLP-1 and GIP, is biased towards the insulin signalling pathway and can be orally formulated
This proactive approach means identifying risks before symptoms emerge, allowing preventive dietary or supplementation strategies
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