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Because GLP-1 therapies delay gastric emptying, temporary discontinuation is recommended prior to procedures requiring anesthesia to reduce aspiration risk [32]
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it has no approved brand name as of mid-2025
(2022) [59] comparing GLP-1RA plus SGLT2i combination therapy to GLP-1RA and SGLT2i monotherapies among 1,895 patients with T2DM enrolled in 8 RCTs, the addition of a GLP-1RA to SGLT2i treatment showed that drug discontinuation, diarrhea, injection-site-related events, nausea, vomiting and genital infections were more likely to occur in combination therapy
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