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While scientists dont know exactly how caffeine works in the brain, the running theory is that it binds to adenosine receptors, preventing a typically adenosine-induced slowdown of wake-promoting brain regions

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COX-1 and COX-2 Inhibition COX-1 Inhibition: This impacts protective prostaglandins that maintain the stomach lining and support kidney function and platelet aggregation (blood clotting)

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Marine Mammal Ecotoxicology: Academic Press

It typically remains stable for about 1014 days, but always refer to your providers guidance for the exact duration