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In animal models, semaglutide reduces food intake and body weight by activating Adcyap1-expressing neurons in the dorsal vagal complex, a key integrator of gutbrain signals that induce a reduction in food intake via both homeostatic and hedonic pathways [78]
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Ipamorelin stimulates the pituitary to release endogenous GH, preserving the natural pulsatile secretion pattern
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