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Systemic allergic symptoms require more urgent attention and include: Cutaneous manifestations : widespread urticaria (raised, itchy welts), generalised pruritus, flushing, or angioedema affecting the face, lips, tongue, or throat Respiratory symptoms : shortness of breath, wheezing, throat tightness, or stridor (high-pitched breathing sound) Gastrointestinal symptoms : nausea, vomiting, abdominal cramping, or diarrhoea (though these can also be common non-allergic side effects of GLP-1 agonists) Cardiovascular symptoms : dizziness, light-headedness, rapid or weak pulse, or feeling faint Anaphylaxis represents the most severe form of allergic reaction and is characterised by the rapid onset of symptoms affecting multiple organ systems

(accessed January 10, 2025)

J Clin Endocrinol Metab 108:24472469 Towbin H, Staehelin T, Gordon J (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

How Long Is Reconstituted GHK-Cu Stable

Debido a lo anterior, la incidencia descrita en la literatura tambin es variable

Clinical trials were satisfactory and the peptide was approved and marketed for therapy as the first GLP-1 receptor agonist in 2005