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The most credible large-scale trial to date found no effect, and my personal logs back that up

Spontaneous Tumor Lysis Syndrome in an Adenocarcinoma of Unknown Origin

JNK1/2 (c-Jun N-terminal kinases) show slight inhibition with reduced phosphorylation, though effects are less pronounced than p38 MAPK pathway changes

However, the absence of long-term data means exercising appropriate caution with extended use

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All of these factors can contribute to poor production of glutathione (or of the enzymes that help glutathione to do its work), and many also deplete the GSH that the cells produce (by converting it into GSSG)