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For example, certain probiotics (e.g., lactobacilli ) reportedly activate the NRF2 pathway via metabolic routes [148], while some pathogens (e.g., Salmonella , Helicobacter pylori ) activate NOX1, upregulate ROS, and induce inflammation [149]

The Centers for Medicare & Medicaid Services reports that $4.9 trillion is spent annually on healthcare expenses in the U.S., yet populations continue to experience rising rates of chronic illness, obesity, and medication dependency, prompting the shift toward preventative longevity medicine

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For decades, doctors relied on stethoscopes, chest X-rays, and clinical intuition to figure it out