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The long-term weight loss effect of GLP-1RAs has also been validated in a recent large-scale clinical trial, which reported a weight loss up to 20.9% after 72-week treatment of tirzepatide [22]
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It mimics the action of GLP-1 (glucagon-like peptide-1), a hormone that regulates blood sugar levels and appetite
In terms of side effects and tolerability, the advantage goes to Semaglutide
Phentermine is not a GLP-1 agonist
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