Food and Drug Administration drug approval summaries: imatinib mesylate, mesna tablets, and zoledronic acid
Cell culture Human malignant melanoma (A375) cells were obtained from the American Type Culture Collection (ATCC, CRL-1619IG-2) and used within ten passages for all experiments
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People who have heart disease or high blood pressure are at additional risk
To further support the transcriptomic findings, we examined the expression of several representative proteins associated with the implicated pathways