Blood was collected from the tail vein and blood glucose levels was measured before the injection and 4, 8, 10, 24 and 48 h after dosing in fed conditions
As a rule of thumb, molecules that cross skin passively are small and fat-soluble
There is no magic pill or injection that will change your metabolism or your habits
Circulating GLP-1 from diet and lifestyle has a half-life of 1-2 minutes before being inactivated in our bodies (Mozafariun et al 2025
A look at people with psoriatic disease regulating body weight with GLP-1 drugs
Therefore, while GLP-1RAs may represent a promising therapeutic option for managing psoriasis, further high-quality studies are needed to distinguish whether the therapeutic effects of GLP-1RAs originate from the direct regulation of immune cells or improvements in comorbidities such as obesity or diabetes