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In August 2025, the FDA granted accelerated approval to semaglutide for adults with metabolic dysfunction-associated steatohepatitis, or MASH, with moderate to advanced fibrosis, making it the first GLP-1 receptor agonist approved for this serious liver condition [8]
The STEP 1 trial, for example, found that the average weight loss over 68 weeks was 14.9%
Simmons, G
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P -values were derived from paired comparisons between placebo and pomegranate interventions using paired t -tests for AUC and Wilcoxon signed-rank tests for all other pharmacokinetic parameters
The validity of the Hospital Anxiety and Depression Scale
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