While further research is needed, liraglutide may work through various mechanisms, such as reducing inflammation in the brain, lowering insulin resistance and the toxic effects of Alzheimers biomarkers amyloid-beta and tau, and improving how the brains nerve cells communicate. Edison added that those in the study who received liraglutide had nearly 50% less volume loss in several areas of the brain, including frontal, temporal, parietal and total gray matter, as measured by MRI
The FDAs announcement that tirzepatide is no longer in shortage means compounding is now tightly restricted, and pharmacies may only prepare the medication for patients with verifiable clinical need that cannot be met by the FDA-approved formulation
Unlike niacin, niacinamide does not cause flushing or uncomfortable warmth
However, every person is different and experiences pain differently, so your experience may vary
Serious side effects (such as pancreatitis with GLP-1 agents, occurring in ~0.1% of patients) are rare
I think that could be an alternate explanation to the extremely low levels of concomitant use of incretin-mimetic drugs with psychedelics.