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These include orlistat, phentermine-topiramate (FDA-approved only), naltrexone-bupropion, liraglutide, setmelanotide, semaglutide, and tirzepatide [9, 10]

Some are curious

Others may develop hypothyroidism after thyroid surgery, radiation treatment for cancer, or because of certain medications

Tesamorelin is typically stronger for fat reduction and metabolic improvement , whereas ipamorelin is gentler and often used for recovery, sleep, and overall wellness

Its mechanism involves reducing hepatic glucose production and improving insulin sensitivity, which indirectly affects appetite and fat storage

Doctors warn that complications can be worse if the drugs are misused, for example, taken to lose a few pounds or bought from unregulated online sellers