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Overview of iron metabolism in health and disease
In clinical trials, retatrutide has shown larger average weight reductions (~30%) than tirzepatide (~21%) or semaglutide (~15%), which researchers attribute to its additional glucagon receptor activity
A semaglutide regimen will also lead to healthier blood sugar levels, which can help you feel more energetic throughout your day
This dual mechanism is why tirzepatide produces greater weight loss in clinical trials and why the dosing numbers look completely different
Its kind of like when youre getting ready to go see the next Marvel movie
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Malhotra A et al., SURMOUNT-OSA, NEJM 2024 (NEJMoa2404881, PMID 38912654) : tirzepatide and obstructive sleep apnea, AHI -25,3 to 52 weeks
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