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In apoptosis, -sitosterol upregulates pro-apoptotic factors such as p53 and Bax, while downregulating anti-apoptotic proteins such as Bcl-2, leading to an increase in mitochondrial outer membrane permeability and the activation of key apoptotic enzyme cascades such as caspase-9 and 3, which induces programmed cell death (83)
Adipokines as an important link between hidradenitis suppurativa and obesity: a narrative review
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7 BlundellJ.FinlaysonG.AxelsenM.FlintA.GibbonsC.KvistT.et al (2017)
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