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10.1007/s00259-009-1363-y CrossRef Google Scholar View reference in article 10 BromM.Woliner-van der WegW.JoostenL.FrielinkC.BouckenoogheT.RijkenP.et al (2014)
Figure 2: Novel Incretin Mimetic Assets for T2DM and Obesity in Phase 2/3 of Development Remaining Unmet Needs Remaining Unmet Needs Though the value proposition of on-market GLP-1 and dual-agonists is strong, several key unmet needs still exist for incretin mimetics across diabetes and obesity, namely: (1) improved efficacy, (2) better tolerability, (3) more convenient options / alternative ROAs, and (4) improved access and affordability
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Reduce the risk of kidney disease progression , kidney failure, and cardiovascular death in adults with type 2 diabetes and chronic kidney disease (CKD) a new and notable expanded indication
Three tretinoin strengths let you titrate irritation vs efficacy 3
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